Scientist Holding Small Formulation
Reproducible and Scalable Nanoparticle Research and Development
Using NanoAssmemblr® technology, develop a broad range of nanoparticle formulations, varying in size, payload and excipient characteristics. Find new designs for difficult-to-deliver drugs and hard-to-treat targets.


Particle Type
Active Ingredients
Nucleic Acid
Peptides and Proteins
Small Molecules
Imaging Contrast Agents
Carrier Materials
LNP
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  • Ionizable lipids
  • Phospholipids
  • Cholesterol
  • PEG-Lipids
Liposomes
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  • Phospholipids
  • Cholesterol
  • PEG-Lipids
Polymer
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  • Poly-lactides (ex: PLGA)
  • Block copolymers (ex: PEG-b-PLGA)
  • Polysaccharides (ex: chitosan, cellulose)
Emulsions
Emulsion
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  • Triolein/POPC
  • Oil/Surfactant
Organic / Inorganic NPs
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  • Lipids
  • Noble metal NPs
  • Rare Earth Metals
  • III-V semiconductors
Exosomes
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  • Natural cell-derived lipids and proteins
  • Additional synthetic lipids and biomolecules
颗粒类型
活性成分
核酸
多肽和蛋白质
小分子物质
造影剂
载体材料
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  • 可电离脂质
  • 磷脂
  • 胆固醇
  • PEG 脂质
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  • 磷脂
  • 胆固醇
  • PEG 脂质
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  • 聚乳酸(如PLGA)
  • 嵌段共聚物(如PEG-b-PLGA)
  • 多糖(如壳聚糖、纤维素)
乳剂
Emulsion
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  • 三油酸甘油酯/POPC
  • 油脂/表面活性剂
有机/无机纳米颗粒
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  • 脂质
  • 贵金属纳米颗粒
  • 稀土金属
  • III-V 族半导体


Precision NanoSystems technology has enabled the development of a broad range of nanoparticle formulations, varying in size (20nm to 200nm), payload (e.g. nucleic acids, hydrophobic drugs) and excipient characteristics (e.g. charge and pH tuning). With the ability to iterate and tune particle characteristics faster than before, researchers are finding new designs and opening up possibilities for targets and drugs that previously would have been difficult or taken too long to develop.

In addition to the above, other particle types have also been developed on the NanoAssemblr® platform.

Particle TypeCompositionRelated Resources
NiosomesNon-ionic surfactant-based VesicleView Paper
Nano-lipomerHybrid particles made of lipids and polymers View Paper
Dendrimer NanoparticleModular biodegradable dendrimer carrying miRNAView Paper

Related Publications

Publication - Abstract

July 01, 2020

Journal of Controlled Release

Delivery of Self-amplifying mRNA Vaccines by Cationic Lipid Nanoparticles: The Impact of Cationic Lipid Select...

G. Lou, G. Anderluzzi, S.T. Schmidt, S. Woods, S. Gallorini, M. Brazzoli, F. Giusti, I. F...

Read More 阅读更多

Publication - Abstract

May 08, 2020

Vaccines

Investigating the Impact of Delivery System Design on the Efficacy of Self-Amplifying RNA Vaccines

G. Anderluzzi, G. Lou, S. Gallorini, M. Brazzoli, R. Johnson, D.T. O'Hagan, B.C. Baudner a...

Read More 阅读更多

Publication - Abstract

April 02, 2020

Journal of Controlled Release

Design of a Novel Vaccine Nanotechnology-based Delivery System Comprising CpGODN-protein Conjugate Anchored to...

D. Chatzikleanthous, S.T. Schmidt, G. Buffi, I. Paciello, R. Cunliffe, F. Carboni, M.R. Ro...

Read More 阅读更多
Resource Center 资源中心

Related Resources

Poster

September 01, 2022

Scale Up Genome Editing of CAR T Cells using Lipid Nanoparticles

Read More 阅读更多 PDF

Application Note

March 15, 2022

Genome Editing of Human Primary T Cells with Lipid Nanoparticles

Read More 阅读更多 PDF

Application Note

January 16, 2019

mRNA Lipid Nanoparticles: Robust low-volume production for screening high-value nanoparticle materials

Read More 阅读更多 PDF
Resource Center 资源中心

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To learn how Precision NanoSystems accelerates nanomedicine development from an idea to clinical applications, contact our Technical Sales Team.

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