November 09, 2016
Neuro9 Kits: Cellular Transfection
Efficient RNA delivery to neurons via ApoE-mediated cell uptake. Neuro9 nanoparticles mimic the behavior of low density lipoproteins LDLs by co-opting Apolipoprotein E ApoE to mediate uptake into cells via the LDL receptor LDLR. As a result, RNA is delivered to neurons with high efficiency over 96%, and cell viability is dramatically improved compared to chemical and physical transfection.