New Developments in Liposomal Drug Delivery


Authors: B.S. Pattni, V.V. Chupin and V.P. Torchilin

Journal: Chemical Reviews

DOI: 10.1021/acs.chemrev.5b00046

Publication - Abstract

October 14, 2015

Hematology Targeted Drug Delivery Small Molecule Drugs

Abstract:


Described first in the 1960s by Bangham1 and understood as a potential drug delivery system in the early 1970s,2−4 the liposome has since become integral to research and clinical applications in the field of nanomedicine. Five decades of research in the field of liposome research have shown their prospective benefits in the medical and cosmetic5−7 as well as the food industry.8,9 Several promising small molecule drugs and genes previously deemed less than useful due to problems of stability, solubility, and nonspecific toxicity can now be delivered to the intended sites of action with the help of nanocarriers like micelles, nanoparticles, and liposomes.


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