Publication - Abstract
Nov 10, 2019
Journal of Controlled Release
N. Veiga, M. Goldsmith, Y. Diesendruck, S. Ramishetti, D. Rosenblum, E. Elinav, M.A. Behlke, I. Benhar, and D. Peer
Interferon regulatory factor 8 (IRF8) protein plays a critical role in the differentiation, polarization, and activation of mononuclear phagocytic cells. In light of previous studies, we explored the therapeutic potential of IRF8 inhibition as immunomodulatory therapy for inflamm...
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Publication - Abstract
Aug 11, 2020
Journal of Controlled Release
K. Lee, T.S. Kim, Y. Seo, S.Y. Kim and H. Lee
Combined hybrid of siRNA tailed mRNA (ChriST mRNA) functioned as siRNA and mRNA to simultaneous suppress and express protein.
siRNA and mRNA structures were separated from the ChriST mRNA by RNase H-mediated cleavage of RNA/DNA ...
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