Publication - Abstract
Jun 23, 2020
Advanced Functional Materials
H. Tanaka, T. Takahashi, M. Konishi, N. Takata and H. Akita et al.
RNA‐based therapeutics is a promising approach for curing intractable diseases by manipulating various cellular functions. For eliciting RNA (i.e., mRNA and siRNA) functions successfully, the RNA in the extracellular space must be protected and it must be delivered to the cytopla...
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Publication - Abstract
Feb 24, 2020
Pharmaceutical Research
S.M. Figueroa, D. Fleischmann, S. Beck and A. Goepferich
A model water-soluble drug lacking ionizable groups, pirfenidone (PFD), was encapsulated through nanoprecipitation in poly(ethylene glycol)-poly(lactic acid) (PEG-PLA)-poly(lactic-co-glycolic acid) (PLGA) NPs. Firstly, the thermodynamic parameters predicting drug-polymer miscibil...
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